Tri Mix

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What is Trimix and other Frequently Asked Questions.

What is Trimix?

Trimix is a compounded combination of three drugs that is traditionally used for erectile dysfunction. The three drugs are alprostadil (prostaglandin), phentolamine and papaverine. The combination is usually injected prior to intercourse and is intended to cause vasodilation (expansion of the blood vessels) to help with erectile dysfunction.

Where can I purchase Trimix?

Trimix can not be purchased at all pharmacies. Only specialized pharmacies the provide sterile compounding services are able to properly make the injection. A list of these pharmacies is available on our site. Click here to be taken to the list of approved pharmacies.

How much does TriMix usually cost?

The cost of the therapy depends on many factors including the strength, quantity, and dose required. As of 2011 the average cost of TriMix for a 5ml vial was about $99. This 5ml vial could provide an average of 30-35 doses to the average patient. This makes TriMix one of the least expensive options available for patients with Erectile Dysfunction.

Does TriMix require a prescription?

Yes, Trimix does require a prescription from your physician. Please feel free to direct your physician to our site for additional information or have him/her contact one of our participating pharmacies to speak directly with a compounding pharmacist. If you are interested in having one of our pharmacies contact your physician on your behalf please contact the pharmacy directly.

How is Trimix injected?

We have provided a step by step, recommended instruction page. Click here to be directed to that page.

Who can I contact if I have additional questions? has a full time Pharmacist available to answer your questions. If you would like to e-mail a question to our pharmacist click here. If you would like to recommend a question for our "What is Trimix and other frequently asked questions" page we would like to hear from you.


The information on this website if purely informational and should not be used to diagnose, cure or treat any patient without the direction and supervision of a physician. If you are intersted in using Tri-Mix or any other treatment for erectile dysfunction make sure to check with your physician first. This and any therapy should be individualized for you by a prescribing physician that knows you, your medical history, and any current and prior medication history. Tri-Mix is not approved by the FDA for the treatment of Erectile Dysfunction and does require a prescription that can only be filled at a compounding pharmacy.

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